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Issue 9: Entwined 28 October 2025 This issue takes a moment to revel in the science that surrounds us. Come walk the tangled paths less followed, who knows what you may come across! Editorial Unravelling the Threads: From the Editors-in-Chief & Cover Illustrator by Ingrid Sefton, Aisyah Mohammad Sulhanuddin & Anabelle Dewi Saraswati A word from the Editors-in-Chief, and fascinating insights into this issue's cover. Knot theory Knot Theory and Its Applications. Why Knot? by Ryan Rud Untangle the knot theory with Ryan to reveal the role of this mathematical marvel in our everyday life. Hugging Entwined: A Hug Story by Elise Volpato Embrace the physiology, psychology and cultural complexities of hugs, as Elise opens us up to their undeniable benefits. Geological time periods Enter . . . the Anthropocene? by Rita Fortune Rita digs into questions of how and where we can draw a line in the sand, in attempts to disentangle a new geological time period. Cosmic matter The Cosmos in Our Palms: A Reflection of Our Cosmic Origins by Mishen De Silva Gain a new appreciation with Mishen of how the beauty and mystery of the cosmos is not just among us, but within us. Humans of UniMelb Rewilding Our Cities with Dr Kylie Soanes by Ciara Dahl Uncover life behind and between the concrete jungle, as Ciara talks all things urban ecology with Dr Kylie Soanes. Brain connectome Conferring with Consciousness by Ingrid Sefton Me, myself and my brain - Ingrid traverses the neural paths that comprise the conscious experience. Journey of food The Life of Matcha by Kara Miwa-Dale Delicately grown, globally consumed: Kara evaluates the intersection of matcha's deep-rooted social importance with physical health and current trends. Gunpowder Ancient Asian Alchemy: Big Booms by Isaac Tian Aiming for immortality, landing at gunpowder? Isaac explores how a quest for life is fundamentally entangled in the alchemy of gunpowder. Classical biology Eyeballs, a Knife, and No Fear of God by Jess Walton Travel back in time with Jess to meet the early anatomists who helped pioneer the arduous and neverending human quest to seek answers from deep within ourselves. Literally speaking, that is. Axolotls Axolotl: The Little God of the Lake by Danny He Dive into the history, habitat, and hardhsips of your favourite frilly friends. Axolotls are so much more than a cute face, and time may be running out to save them. Camouflage Living Pixels by KJ Srivastava Uncovering the science behind camouflaging creatures that have no eyes makes this trick no less magical, as KJ reveals. Pacific Island futures Human-Cetacean Relations by Andrew Irvin Taking us to Tonga, Andrew tells a tale of a musician swimming between the worlds of communication, marine science and a future for Pacific Islands. Philosophy of science It’s Dangerous to Go Alone by Julia Lockerd Join Julia to debate the importance of epistemic and social relationships in the development of modern science. Perceptions of time Time Perception – The Chaos Binding Your World Together by Furqan Mohsin Spend a moment with Furqan considering how our perception of time strings us together, yet fundamentally pulls us apart.

Issue 8: Enigma 3 June 2025 This issue unspools the long-hidden threads in science. Come make sense of the puzzles and mysteries with us! Or perhaps, leave just as addled. Editorial Cracking the Code: A Word from the Editors-in-Chief by Ingrid Sefton & Aisyah Mohammad Sulhanuddin A word from our Editors-in-Chief. Facial recognition Friend or Foe?: The Mechanisms Behind Facial Recognition by Mishen De Silva What's in a face? Mishen walks us through the ingenious ways our brains make meaning of the faces we see everyday. Human evolution The Lost Link: A Mystery in Evolution by Eymi Gladys Carcamo Rodriguez The theory of human evolution conjures textbook timelines of ape to man, but as Eymi explores, biology has never been that simple. Celebrity culture Glowing Limelight, Fashioned Stars by Aisyah Mohammad Sulhanuddin Chronically online or not, society sure loves its stars. Aisyah investigates the messy sociology behind our relationships with celebrities in past decades. Astronomy Why Are We So Fascinated by Space? An Exploration of Human’s Fascination with Outer Space by Emily Cahill What make the night sky impossible to ignore? Emily uncovers how culture, commercialisation and science have fuelled our cosmic curiosity. Prehistoric predators Terror Birds: The Discovery of Prolific Hunters by Jason Chien Giant, flightless and carnivorous - Jason pieces together the rise of terror birds as fearsome apex predators Psychology A Psychological ‘Autopsy’ of Ludwig van Beethoven: Dissecting Genius and Madness by Kara Miwa-Dale Elusive and erudite, even beyond the grave. Dissect the inner world of Beethoven with Kara - when can we call genius, madness? Fungi Fungal Pac Man by Ksheerja Srivastava No matter how good of a gamer you are, Ksheerja proves why biosensensing fungi should be crowned as our worlds best Pac-Man player. Dreams In Your Dreams: Unpacking the Stories of Your Slumber by Ciara Dahl Where do our minds go every night? Ciara explores the mysterious science best theories behind dreaming Neurology Functional Neurological Disorder by Esme MacGillivray What if your nervous system just stopped working? Esme explains FND, and how it affects someone, beyond symptoms. Slime moulds Thinking Outside the Body: The Consciousness of Slime Moulds by Jessica Walton I think, therefore I am... a slime mould? Jess ponders whether this humble, single cell protist may exhibit conciousness without a brain. Psychadelics Life Story of a Drug by Elijah McEvoy From 'Bicycle Day' to brain receptors, Elijah takes us on a trip through the enigmatic origins, uses and psychadelic effects of LSD. Gut microbiome Microbic Mirror of The Self by Sarah Ibrahimi Microbes: Humanities greatest enemy or our best friend? Sarah explores the relationship between the gut microbiome and our health. Infantile amnesia Mental Time Travel: How Far Can I Remember? by Sophie Potvin Step inside the hippocampus, as Sophie illustrates the mechanisms of memory formation and our power to make the past come alive again. Consciousness A Headspace of One’s Own by Andrew Irvin At what point does a computer become conscious? Andrew delves into technology that blurs the line between artificial intelligence and the human brain. Prejudice in Science What Do Women Want? by Madeleine Kelly The question we should be asking is not what we know, but what we don't know about women.

Issue 10: Fact & Fiction 2 June 2026 This issue traverses the boundaries of truth, certainty and fabrication. Join us to illuminate the myriad grey space that lies in between. Editorial Shining Light on the Grey by Ingrid Sefton, Kara Miwa-Dale and Anabelle Dewi Saraswati A word from the Editors-in-Chief and some enlightening insights from this Issue's Cover Illustrator Biological evolution That Protein is AI, Dude by KJ Srivastava Move over nature, is artificial intelligence the new apex predator of protein evolution? Determinism and indeterminism Contingent Realities - the (Ph)ailure of a (Ph)act by Edmond Sim From Plato to quantum mechanics, Edmond muses whether objective facts truly exist — or if reality depends on who's observing it. Climate change To Prevent Climate Catastrophe, Keep Reading by Madeleine Kelly Madeleine argues its time to rewrite the landscape of climate fiction from one of impending doom into one of hope and action. Paleontological reconstructions Terrible Lizards and their Terrible Reconstructions by Kaya Czerwinska A flying Stegosaurus, upside-down Hallucigenias: Kaya revisits palaeontology's most delightfully bizarre mistakes. Traditional Chinese medicine The Human Body: A Portrait Painted by a Thousand Minds by Isaac Tian Isaac examines how different cultures have attempted to answer the same timeless question: how does the human body truly work? Neuroscience When Fiction Feels Real: How the Brain Builds Reality by Terra Gi Where does reality exist: in the world, or in our mind? Terra probes how the brain blurs the boundaries of perception and experience. Genetic engineering The Predictions of Genomics: Fictions Once Called Fact by Scarlett Yang Beyond mere educated guesses, precision in scientific prediction is paving the way forward in genomic innovation. Little scientists Young Scientists in the Making by Kacy Toombs Cultivating curiosity in children is not only considerate, but fundamentally scientific, Kacy posits. Biobanks How Population Biobanks Shed Light on Disease by Jason Chien Jason unlocks how biobanks are helping researchers probe new insights into human health and disease. Sex differences Unpacking Myths: Distortions of Sex Differences in Popular Culture by Vicenta Wheatley From dating podcasts to TikTok algorithms: how science on sex differences is simplified, sensationalised, and sold. Time travel Reimagining Time: From Relativity to Wormholes by Zahra Halela If time is relative, bending the bounds of physics and reality, Zahra considers how far-fetched the notion of time-travel really is. Truth under AI Are Truths Possible Under AI? by Vanessa Cheng As AI blurs the line between truth and deception, Vanessa considers how it is changing the way we see the world. Opposites attract Dating Isn’t Physics – Opposites Don’t Attract by Elva Assisan Elva repels the theory that our magnetic pull towards the trope of "opposites attract" is founded in science. Misinformation Fiction Disguised as Fact: The Cost of Scientific Misinformation by Kara Miwa-Dale Vaccines save lives — but as Kara explores, misinformation can undermine them just as powerfully.

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< Back to Issue 4 Echidnas: Gentle Courters In The Competitive Animal Kingdom by Emily Siwing Xia 1 July 2023 Edited by Maddison Moore and Arwen Nguyen-Ngo Illustrated by Christy Yung When we think of animals or nature in competition, we picture aggression and savagery over resources such as food, territory and mates. Beyond aggression, however, the variety of animal behaviour associated with competition for resources is immense. A gentle form of competition is the bizarre mating ritual of our own unique Australian fauna: the echidna. Known as Tachyglossus Aculeatus and spiny anteaters, echidnas are quill-covered animals living in Australia and New Guinea. Since Australia is so isolated from other continents, our fauna has often been regarded by outsiders with an air of mystery and awe. To start with, echidnas are in the same family as the famed platypus, called monotremes (egg-laying mammals). Surviving monotreme species can only be found in Australia and New Guinea. The four species of echidnas, along with their duck-billed cousin, are the very few surviving members in this classification. Despite the similarities in their name and appearance in both being covered with hollow, spiny quills, these spiny anteaters are not actually closely related to the more well-known anteaters in the Americas on a genetic and evolutionary basis. Echidnas feed on a diet of ants and termites, using their electroreceptive beaks to find burrowing prey digging them out with their hind claws. These powerful claws are long and curved backwards, specially designed for digging. Funnily, when the British Museum received an echidna specimen, they switched the backward claws frontwards thinking that it was a mistake. As mentioned before, mating rituals can be a violent (even bloody) ordeal in nature. From barbed penises in cats and deadly fights for females in elephant seals, straight to sexual cannibalism in praying mantises, there seems to be endless examples of brutality in the animal world. However, behind these brutal images is another side of nature that seems gentle and even humorous at times: for example, the ritual of our spiny suitors. Echidna mating rituals begin with the formation of a mating train. From June to September in Australia, male echidnas mate by lining up — from their beak tips to their spiny bottoms — to follow behind one single female. These trains can have more than 10 males in line and last for days, even weeks, at a time. During the mating season, male echidnas may leave a train to join or form a different train behind another eligible female. Their mating efforts often lead males to travel for long distances, even beyond their own home ranges. If the males get interrupted and lose track of the female, they reform their train by picking up her scent with their snouts in the air. They are such determined suitors that it is extremely difficult for a female echidna to evade them. Usually, there is one male that remains through the long-winded process, and they get to mate with the female. The reason behind forming echidna trains is unknown, but scientists generally agree that it is correlated with some type of selection process. One theory is that it aids the female in weeding out all the weaker males by tiring them out until the last one remains. Another is that the female is waiting for the right male that she is interested in to get behind her. Either way, it is a process of determination and perseverance. In exceedingly rare occasions where there are still multiple suitors left at the end, the males dig a trench surrounding the female and compete through head bumping. Although there is still much not understood about head bumping due to its scarce occurrence, it is generally considered an echidna social behaviour that serves to maintain dominance. Head bumps are generally only given by dominant echidnas to subordinate echidnas who haven’t recognised their dominance status and moved away. This rarely happens and is a relatively peaceful affair compared to conflicts in other animals. The winner of the mating head bumping ritual then digs until the previously mentioned trench is deep enough for him to be below the female so they can mate through their cloacas. 23 days after copulation, the female lays a soft-shelled leathery egg into a temporary pouch where it continues to incubate for 10 more days when a tiny puggle (a baby echidna or platypus) hatches. The puggle drinks milk from the female’s special mammary hairs until it is capable of feeding itself and has fully covered spines and fur. At last, the matured echidna leaves their mother’s burrow to live independently. The mating rules and practices amongst echidnas are a demonstration of patience and courtesy. This contrasts with the general public misconception of nature being merciless, which is characterised by the brutal competition for food, social status and mating opportunities. Although they are in the same competition for a mate, the lines of waddling echidnas are polite, organised and humorous. Behind the mask of brutality, nature continues to have its pleasant secrets. References Morrow G, Nicol SC. Cool Sex? Hibernation and Reproduction Overlap in the Echidna. PLoS One. 2009 Jun 29;4(6):e6070. Echidna [Internet]. AZ Animals. [cited 2023 Jun 22]. Available from: https://a-z-animals.com/animals/echidna/ Anne Marie Musser. Echidna | Britannica [Internet]. 2023 [cited 2023 Jun 22]. Available from: https://www.britannica.com/animal/echidna-monotreme Echidna trains: explained [Internet]. Australian Geographic. August 6, 2021 [cited 2023 Jun 22]. Available from: https://www.australiangeographic.com.au/topics/wildlife/2021/08/echidna-trains-explained/ Lindenfors P, Tullberg BS. Evolutionary aspects of aggression the importance of sexual selection. Adv Genet. 2011;75:7–22. Warm Your Heart With Videos of ‘Echidna Love Trains’ [Internet]. Atlas Obscura. September 1, 2017. [cited 2023 Jun 22]. Available from: http://www.atlasobscura.com/articles/echidna-love-trains Previous article Next article back to MIRAGE

< Back to Issue 5 A Message from the Editors in Chief Rachel Ko & Ingrid Sefton 24 October 2023 Edited by Committee Illustrated by Aisyah Mohammad Sulhanuddin “There are known knowns. These are things we know that we know. There are known unknowns. That is to say, there are things that we know we don't know. But there are also unknown unknowns. There are things we don't know we don't know.” - Donald Rumsfeld Science should never be considered as pursuing absolute truth. In fact, more often than not, the deeper we dive into its exploration, the more questions that arise. The world of science affords us choices in how we appropriate the understandings and knowledge gained in its study. Every day, science pushes us to tiptoe this fine line between pushing boundaries and crossing them altogether. It is perhaps this unknown that makes the pursuit of science so wicked in itself, taunting us with the promise of making the next big discovery, or finally finding the cure to cancer. But it is also what drives us, entrances us, and keeps our desire for knowledge burning — it’s edge-of-your-seat exciting. At its onset, we envisioned this issue as a chance to probe the mysterious nuances of science — a peek into the ‘Wicked’ness of the world. Seeking to ask questions of the ethical, the malicious and the unknown, contributors were inspired to delve into the darker sides of science. Each article ventures into the limits of what we do, and, just as importantly, don’t know in this ever-evolving field. The word Wicked in itself is a complex character, begging for ambiguous interpretation. Is there such a thing as pure evil? Are we all, just a bit, inherently wicked? What makes something wickedly cool? (Was Kristin Chenoweth’s Glinda the best portrayal that Broadway could ask for?) And so, in the hands of our creators, something wicked this way comes … As with every edition of our magazine, each piece has been created, edited and illustrated entirely by students. This issue continues to stand true to our aim of providing a platform within, and beyond, the university community for students of all backgrounds to craft their science communication skills in a supportive, creative environment. Countless hours have been poured into the curation of each edition with the hope of making innovative science content easily accessible — so please, enjoy! To all our passionate, dedicated contributors - thank you for the time you have invested in crafting the wonderful, wicked world of Issue 5 of OmniSci. It has been a privilege to watch the collaboration of inquisitive minds, from diverse scientific and artistic worlds, produce this collection of work. We also wish to extend our gratitude to you, our wonderful readers, in your ongoing support of OmniSci. The time you give to reading and engaging with our student-driven magazine does not go unnoticed, motivating and inspiring us for our future endeavours. Now, take a moment, and come venture into the Wicked world of Issue 5 with us… Wicked back to

< Back to Issue 2 How to use a time machine Whilst time travel is thought to be nothing more than science fiction, the very laws of physics point to its possibility. Physicists have long sought the answer to such a phenomenon using knowledge from rockets to generating wormholes. by Sabine Elias 10 December 2021 Edited by Niesha Baker Illustrated by Quynh Anh Nguyen So you have just entered the TARDIS machine and are trying to work out how to use it to travel to the past to re-write the present and save the future? Well, look no further because you have come to right place. In this article, I will be describing how to jumpstart your time traveling vehicle and by the end, you will be proficient in navigating your way through the universe and evading time. Do be warned however, that batteries are not included and the simulation may crash at times. Now, you are probably wishing that you could travel back in time to have not clicked this article and saved yourself these two minutes of life that you will never get back. But is time travel really a possibility? We often think about the world as a state of order. Social and political constructs generally keep society running in a systematic manner. But what if I told you the entire universe came to exist from disorder? Before we get to logistics, let me introduce you to a little something known as ‘entropy’. Entropy describes the state of disorder (1). Take a closed bottle containing gas. Once you open this bottle, the gas will diffuse out into the open space with no way to retrieve it in the exact same state back inside the bottle. In essence, this gas has become ‘disordered’ and thus its entropy has increased. For years, scientists have understood that the entropy of the universe is always increasing, which means that stars, planets and galaxies are in constant motion away from each other (1). If we wanted to travel back in time, we would essentially have to reverse every single chemical reaction that has occurred from the point in time we currently stand in, to the point in time that we wish to travel to (2). This is theoretically impossible as we would be violating the laws of physics and decreasing the entropy of the universe but we still do not know if it is physically impossible. Let Brain Cox explain: Another problem with time travel would be altering events of the past. Take the Grandfather Paradox: if someone travelled back in time to kill their ancestor, then the possibility of their existence in the future would be zero (3). Thus, they would have been unable to time travel to begin with to have killed their ancestor. This issue of causality is expanded upon through the Novikov Self-Consistency Principle (4). This states that if an event causes a paradox or changes the past, the possibility of this event occurring would be impossible. However, this principle is not widely accepted by time travel enthusiasts. Now, whilst your TARDIS machine may be nothing but a prop at this point in time, it could still help provide evidence on the possibility of time travel. Take this example: you set up two duplicates of the same clock that read the same time and placed one into a rocket that blasts off into space. The rocket orbits around the Earth and then returns and is compared to the clock that remained on Earth. You would find that less time has passed on the clock that was in the rocket. Why? Because moving clocks run slower than stationary clocks. That is, as you move faster through space, you move slower through time. This is known as Time Dilation (5). An example of time dilation is the comparison of time on the International Space Station (ISS) to the time on Earth. Astronauts who have spent 6 months in the ISS have aged 0.005 seconds less than people on Earth (6). This does not seem like much because the astronauts are not traveling close to the speed of light. To see the effects of time dilation multiply, one would need to be very close to the speed of light. If you were to travel in space at 90 per cent the speed of light, whilst everyone on earth would age by 22 years you would only have aged by 9! Speed is not the only thing that affects how fast we age, gravity also affects our experience of time. A stronger gravitational field means that time travels slower in that field. For instance, your feet age slower than your head considering the slightly smaller gravitational pull on your feet compared to your head. Now take a black hole; we know that black holes have immensely strong gravitational fields where one hour near a black hole would equal approximately 100,000,000 years for a person on earth (7). So what would happen if you travelled through a black hole? No one really knows what occurs inside a black hole but we know trying to enter will likely turn you into spaghetti (8). That being said, we can only observe things that go as far as the event horizon of the black hole, so once something has entered it, we do not know what has happened. Black holes have however, been especially useful in theoretically explaining the possibility of time travel. Placing someone in a strong gravitational field or having them experience motions close to the speed of light would have them experience time slower compared to someone on Earth. This brings us to wormholes. Einstein’s theory of general relativity predicts the existence of wormholes which would theoretically permit time travel. To travel to a galaxy that is 2.5 million light years away with the fastest rocket on earth would be impossible as it would take longer than a human lifetime. This is where wormholes come to the rescue. A wormhole would provide us with a shortcut to our location of interest. Imagine folding a paper in half and poking a pen through it to represent your route of travel. You are essentially skipping the length of the paper and traveling from one end to the other. Source: The Independent. (2008). The Big Question: Is time travel possible, and is there any chance (9). You then situate one mouth of the wormhole in a spacecraft traveling close to the speed of light and the other mouth on Earth. If you then went through the mouth on Earth and travelled through to the space craft, you would be traveling back in time. This is because time would be passing much slower at the other end of the wormhole than where you entered from. However, physicists have not yet developed such advanced technology capable of this, but theoretically speaking, this is a possibility if such technology was developed in the future. Whilst you may have thought that time travel was merely based on science fiction, the laws of physics do not forbid its existence. However, here is some food for thought: “If time travel is possible, where are the tourists from the future?” Stephen Hawking Perhaps with time, we may transform this theory into reality. So for the time being, just sit back and enjoy the presence of your TARDIS machine. Perhaps you might even get lost in time from the very thought of time travel. References: 1. Wehrl, Alfred. “General Properties of Entropy.” Reviews of Modern Physics 50, no. 2 (April 1, 1978): 221–60. https://doi.org/10.1103/revmodphys.50.221. 2. BBC. “Brian Cox Explains Why Time Travels in One Direction - Wonders of the Universe - BBC Two.” YouTube, March 10, 2011. https://www.youtube.com/watch?v=uQSoaiubuA0. 3. Smith, Nicholas J.J. “Time Travel (Stanford Encyclopedia of Philosophy).” Stanford Encyclopedia of Philosophy, November 14, 2013. https://plato.stanford.edu/entries/time-travel/#GraPar. 4. Carlini, A., V.P. Frolov, M.B. Mensky, I.D. Novikov, and H.H. Soleng. “Time machines: The principle of self-consistency as a consequence of the principle of minimal action.” International Journal of Modern Physics, no. 05 (October 1995): 557–80. https://doi.org/10.1142/s0218271895000399. 5. The Editors of Encyclopaedia Britannica. “Time Dilation | Explanation, Examples, & Twin Paradox.” In Encyclopædia Britannica, 2019. https://www.britannica.com/science/time-dilation. 6. Dickerson, Kelly. “Here’s Why Astronauts Age Slower than the Rest of Us Here on Earth.” Business Insider Australia, August 20, 2015. https://www.businessinsider.com.au/do-astronauts-age-slower-than-people-on-earth-2015-8. 7. Gharat, Sarvesh Vikas. “Relativity and Time Dilation.” International Journal for Research in Applied Science and Engineering Technology 7, no. 11 (November 30, 2019): 650–51. https://doi.org/10.22214/ijraset.2019.11103. 8. "Death by spaghettification: Scientists record last moments of star devoured by black hole." NewsRx Health & Science, November 1, 2020, 236. Gale Academic OneFile. https://link.gale.com/apps/doc/A639405517/AONE?u=unimelb&sid=bookmark-AONE&xid=6812ee05. 9. “The Big Question: Is Time Travel Possible, and Is There Any Chance.” The Independent, February 8, 2008. https://www.independent.co.uk/news/science/big-question-time-travel-possible-and-there-any-chance-it-will-ever-take-place-779761.html. Previous article back to DISORDER Next article

< Back to Issue 7 Fossil Markets: Under the Gavel, Under Scrutiny by Jesse Allen 22 October 2024 edited by Zeinab Jishi illustrated by Jessica Walton At the crossroads between science and commerce, the trade in fossils has "developed into an organised enterprise" over the course of the twentieth century. With greater investment and heated competition between museums and private collectors, fossils increasingly took their place alongside “art, furniture, and fine wine” (Kjærgaard, 2012, pp.340-344). Fast forward to the twenty-first century, and this trend shows no signs of abating. On the contrary: as of 10 July 2024, a near-complete stegosaurus skeleton - nicknamed ‘Apex’ - was discovered by a commercial palaeontologist in Colorado, and was later purchased by “hedge-fund billionaire” Ken Griffin for US$44.6 million (Paul, 2024). This makes it the single most expensive dinosaur skeleton ever sold, eclipsing the previous record set in 2020 for a T-Rex named ‘Stan’, who was snapped up for US$31.8 million (Paul, 2024). These sales came with their fair share of criticism and controversy, reigniting the long-standing debate about how fossils should be handled, and where these ancient remains rightfully belong. Fossils (from the Latin fossilus , meaning ‘unearthed’) are the “preserved remains of plants and animals” which have been buried in sediments or preserved underneath ancient bodies of water, and offer unique insights into the history and adaptive evolution of life on Earth (British Geological Survey, n.d.). Their value is by no means limited to biology, however: they are useful for geologists in correlating the age of different rock layers (British Geological Survey, n.d.), and reveal the nature and consequences of changes in Earth’s climate (National Park Service, n.d.). Though new discoveries are being made all the time, fossils are inherently a finite resource, which cannot be replaced. This is part of what makes the fossil trade so lucrative, but the forces of limited supply and high demand have also led to the emergence of a dark underbelly. Cases of fossil forgery go back “as far as the dawn of palaeontology itself” in the late 18th and 19th centuries (Benton, 2024). The latest “boom in interest" is massively inflating prices and “fuelling the illicit trade” in fossils (Timmins, 2019). Whereas the US has a ‘finders-keepers’ policy, according to which private traders have carte blanche to dig up and sell any fossils they find, countries such as Brazil, China, and Mongolia do not allow the export of specimens overseas (Timmins, 2019). Sadly, this does little to prevent illegal smuggling; the laws are sometimes vague, and enforcement can be difficult when no single government agency is responsible for monitoring palaeontological activities (Winters, 2024). According to David Hone, a reader in zoology at Queen Mary University of London, “not every fossil is scientifically valuable”; but they are all “objects…worthy of protection,” and too many “scientifically important fossils appear briefly on the auction house website” before “vanish[ing] into a collector’s house, never to be seen again” (Hone, 2024). Museums, universities, and other scientific organisations are finding it more and more difficult to “financially compete with wealthy, private purchasers” as they are simply being priced out of the market (Paul, 2024). As sales become less open to expert scrutiny, the risk of forgery and price distortions become greater. It also has negative implications for future research. Private collectors might give access to one scientist, but not allow others to corroborate their findings. If the fossils aren’t open to all, many institutions simply won’t examine the items in private collections as a matter of principle. (Timmins, 2019). The general public also loses out in a world where dinosaur fossils are reduced to expensive conversation pieces. As Hone writes, “we might never dig up another Stegosaurus, or never find one nearly as complete as [Apex].” Having waited 150 million years to be unearthed, this latest fossil is one of many that may not see the light of day for a very long time. Bibliography Benton, M. (2024, September 5). Modern palaeontology keeps unmasking fossil forgeries – and a new study has uncovered the latest fake . The Conversation. https://theconversation.com/modern-palaeontology-keeps-unmasking-fossil-forgeries-and-a-new-study-has-uncovered-the-latest-fake-223501 British Geological Survey. (n.d.). Why do we study fossils? British Geological Survey. https://www.bgs.ac.uk/discovering-geology/fossils-and-geological-time/fossils/ Hone, D. (2024, June 10). The super-rich are snapping up dinosaur fossils – that’s bad for science . The Guardian. https://www.theguardian.com/commentisfree/article/2024/jun/10/super-rich-dinosaur-fossils-stegosaurus-illegal-trade-science Kjærgaard, P. C. (2012). The Fossil Trade: Paying a Price for Human Origins. Isis , 103 (2), 340–355. https://doi.org/10.1086/666365 National Park Service. (n.d.). The significance of fossils . U.S. Department of the Interior. https://www.nps.gov/subjects/fossils/significance.htm Paul, A. (2024, July 18). Stegosaurus 'Apex' sold for nearly $45 million to a billionaire . Popular Science. https://www.popsci.com/science/stegosaurus-skeleton-sale/ Timmins, B. (2019, August 8). What’s wrong with buying a dinosaur? BBC News. https://www.bbc.com/news/business-48472588 Winters, G.F. (2024). International Fossil Laws. The Journal of Paleontological Sciences , 19 . https://www.aaps-journal.org/Fossil-Laws.html Previous article Next article apex back to

< Back to Issue 10 Young Scientists in the Making by Kacy Toombs 2 June 2026 Illustrated by Saraf Ishmam Edited by Ingrid Sefton When you look at a baby, a multitude of thoughts might cross your mind, ranging from “aww cute” to “ ew, I’m never having kids” . You might see a baby babbling, screaming, drooling, or giving you that heedless, unwavering stare, and think about how silly that baby is. How socially inept! There’s not a thought behind those eyes! But what if I told you that every single baby is actually a young scientist? That everyday, babies are conducting social and scientific experiments; testing the limits of their understanding and noting down the mechanics of our world? Together, let’s explore how everyday babies are deploying the scientific method to learn about the world around them, and how they use these techniques to navigate life. If you’re at all familiar with this magazine, you’ll most likely know exactly what the scientific method entails. For those of you who haven’t touched a science kit since your Year 9 biology class, I’ll briefly explain. The scientific method (also known as the analytical method) is the use of a series of experiments to test a hypothesis. These experiments are often circular in their function, with the hypothesis modified and further retested until consistent results are achieved (1). It is standard practice within the many fields of science, and can range from wildly entertaining social experiments, to closely controlled quantitative observations. In the most basic terms, the scientific method is the art of asking a question, then seeking an answer. Picture a baby in a highchair. They’re happily wobbling their arms and swinging their plump little legs. Maybe they are even dribbling out the remnants of their mushy lunches. They pick up their spoon, and instead of using the spoon for its intended purpose, they drop it onto the floor. There are a number of things happening in this given scenario. A baby isn’t simply dropping the spoon to be annoying or to make itself laugh; though many babies have in the past, and will in the future, think that this act is very, very funny. The baby is asking a question – creating a hypothesis – and testing a number of variables. What happens when I let go of this spoon? When they drop the spoon, they are observing science in action. Gravity – the spoon falls down. Physics – the spoon spins in the air and bounces on the floor. The energy of sound waves – the clattering of the spoon on tile is loud, versus the soft boff of it bouncing on carpet. There are also the social aspects to consider. How will the people around them react? Will they come pick up the spoon? Is this a good way to get somebody’s attention? Like all great scientists, a baby will need to run multiple tests to come to conclusive results, so they will drop a lot of spoons. Now, am I advocating for us to let children throw their spoons around? Of course not. Part of this experience is for children to also learn that throwing spoons at the dinner table isn’t classified as decent behaviour in our society. But I do believe that it is important to acknowledge what a child is doing here. This action stems from curiosity, and it is important to cultivate that curiosity rather than quash it. Curiosity is a common trait we associate with ourselves as a species, and more often than not, is an intrinsic characteristic of children. Ironically enough, science has a hard time pinpointing the ‘why’ behind our curiosity (2), though many theories on the cognitive development of humans link our need to observe the environment and animal behaviour to survival (3). The power of curiosity is a baby’s best tool in their metaphorical toolkit. As a newly conscious being, there’s a lot about the world that they simply don’t understand. There’s a reason why the phrase, “ a baby’s brain is like a sponge” , is so well known. They absorb everything, and are constantly using any newly acquired knowledge to test the limits of their own understanding. The art of observing the world and the willingness to learn from it can be broken down into four main categories: questioning (the act of verbalising curiosity), physical exploration (bodily curiosity as a sensory experience), philosophising (the act of verbalising wonder) and embodied fascination (bodily wonder that does not seek a cognitive answer) (4). Of course, a baby won’t start verbalising their curiosity until they can speak (at which point you might be forced into the repetitive hell of a child’s never-ending echolalia of “ but why?” ), but instinctually the questions are present. These four categories are not mutually exclusive; often wonder can lead to curiosity and curiosity can lead to wonder. When people are given the room to explore their curiosity in any learning institution, they naturally grasp the concepts taught to them with a better understanding (5). Unfortunately, many modern day schools prioritise academic performance over a child’s own understanding of any given topic. I’m sure we can all relate to being talked at by a lecturer in the classroom rather than being invited to participate in the conversation. It’s a pretty fast way to get your brain to switch off and dull any curious inclination you might have had. It is no secret that some children learn differently from others, and this method of simply giving instruction in class can work for some. But using the broadest methods of engaging in wonder and curiosity will help all students, alongside their relationship with learning as a whole (6). Have you ever wondered why children enjoy field trips so much? It isn’t just the novelty of breaking a set routine and ‘skipping’ a school day; it’s also much simpler than that. Field trips give students a safe space to have fun with their learning and actively immerses them in all four categories of wonder and curiosity. Let’s take the example of students going to a planetarium. A child has the opportunity to physically explore a space; by interacting with planet mobiles or using their hands to feel textures on touchable exhibits, children are engaging in their bodily curiosity. Questions are naturally prompted by these physical explorations – “Is this Mars?”, “Which planet is Earth?” – which can lead to further discussions with their teachers and peers. Through these discussions, children can start philosophising certain ideas based on their newly acquired knowledge: “ These space rocks look like rocks on Earth. I wonder if they are made of the same thing?” . And in the quieter moments, children can idly sit with their own embodied fascination, taking in the atmosphere of the universe from inside the cool dome of the planetarium. There are no examinations or grading on field trips. A child has the freedom to simply be. This cultivation of curiosity at such a young age actively helps aid in the development of more complex and abstract thoughts (7) and leads to children in learning institutions taking more intellectual risks when approaching topics unknown to them. There’s a magic in being curious, in this need to fill in the blanks of their own knowledge. When children are comfortable in their own lack of understanding, they are not only more receptive to learning, but are shown to be more flexible in their beliefs when presented with new ideas (8). They engage more in classrooms, they speak up when they don’t understand, and they embrace the discomfort of not knowing. It all starts with the little, nappy-wearing scientist, sitting in their highchair. These babies are setting up their own cognitive learning systems from the moment they open their eyes. They let their curiosity guide their experimentation, which shapes how they come to understand the world. So what if they’re not making any groundbreaking revelations? They don’t need to be. Give in to your own curiosity next time you encounter a baby in the wild. See if you can observe the little scientist in action as they interact with the world for the first time. And hell, maybe let them drop a few spoons. References Gregersen E. Scientific method. Britannica. 24 April 2026. https://www.britannica.com/topic/empirical-evidence Kobayashi K, Ravaioli S, Baranès A, et al . Diverse motives for human curiosity. Nature Human Behaviour. 2019;3:587-595. doi: 10.1038/s41562-019-0589-3 Del Claro K. It All Began Out of Necessity and Curiosity. Behavioral Ecology . 2026;1-10. doi: 10.1007/978-3-032-13988-7_1 Heggen MP, Lynngård AM. Wonder and curiosity beyond the obvious—a dynamic model of bodily and verbal understandings of these phenomena. Humanities and Social Sciences Communications. 2026;13:167. doi: 10.1057/s41599-025-06467-3 Kidd C, Hayden B. The Psychology and Neuroscience of Curiosity.” Neuron. 2015;88(3):449-460. doi: 10.1016/j.neuron.2015.09.010 Peterson EM. Supporting curiosity in schools and classrooms. Behavioral Sciences. 2020;35:7-13. doi: 10.1016/j.cobeha.2020.05.006 Hall S. The Young Child as Scientist. A Learning Moments Collection. Videatives. 2015. https://videatives.com/node/2117 Jirout JJ, Vitiello VE, Zumbrunn SK. Curiosity In Schools. The New Science of Curiosity . Edited by Gordon G., 243-266. Nova, 2018. Previous article back to Fact & Fiction Next article

< Back to Issue 10 Shining Light on the Grey by Ingrid Sefton, Kara Miwa-Dale and Anabelle Dewi Saraswati 2 June 2026 Illustrated by Anabelle Dewi Saraswati Edited by the Editor-in-Chiefs Truth: from that with a little t, to the just out of reach capital T “Truth”. We seek it, we declare it, we believe in it. An innate drive towards answers, embedded in the human process of scientific exploration. Our notions of fact and fiction often feel like black and white binaries with clear boundaries; easily distinguishable, one or the other. Consider an alternative. That science, as in life, is a chiaroscuro of fact and fiction. Shades of light and shadow, which contrast truths and contradictions in order to point us to a clearer, but never fully transparent view of reality. Our scientific methods help us whittle away outright lies, and approach a closer approximation to that of fact than one of fiction. Yet, undeniably, there remains frustratingly little we can say with utmost certainty. History is littered with reminders of how fragile “truth” can be. There was a time when illness was understood as a delicate imbalance of blood, phlegm, black bile and yellow bile. At one point, continents were assumed to be fixed and unmoving, until tectonic plates revealed a restless Earth in constant motion. It is precisely by interrogating these once-settled “facts” that science advanced — not in straight lines, but through disruption, revision, and occasional collapse. And still, there are questions we orbit but have not yet landed on. What exactly is dark matter, which seems to hold galaxies together while refusing to reveal itself? How does consciousness emerge from the quiet electrical choreography of neurons? In these spaces, science is not a catalogue of answers, but a map of known unknowns. A lack of absolutes does not negate the power of science – far from it. Indeed, this is a large part of what drives us to become ever more inquisitive, innovative and critically questioning of the scientific landscape. Ideas once accepted as unquestionable truths can be later overturned through science, just as concepts once dismissed as fantasy may eventually become reality. May this issue urge you to pause, to consider the myriad of grey space that exists in between as you traverse the boundaries of truth, certainty and fabrication. Where does one end, and another begin? A word from the Cover Illustrator Anabelle For this issue’s cover illustration, I was inspired by the history and strange patterns of crop circles. These vast, intricate formations pressed into fields that sit somewhere between scientific curiosity, mass hysteria, art, and folklore; the perfect visual encapsulation for this issue’s theme, Fact and Fiction. Cropping up throughout the late 70s to 80s, they became a cultural phenomenon tied to UFO sightings, conspiracy theories, extraterrestrial speculation, and pseudoscientific fascination. Conceptually, crop circles simultaneously exist as a hoax, artwork, scientific anomaly, and collective myth, depending on the observer. I approached the illustration through a lens of nostalgia, imagining it as the cover of a forgotten children’s mystery book you could stumble upon in an op-shop dating all the way back to the 80s or 90s; sun-faded, slightly eerie, but playful in its wonder. The Midwest-inspired rural scene allowed me to lean into that atmosphere of a quiet blue hour mystery that surrounded alien encounters and paranormal media in the late twentieth century, when crop circles occupied such a strange and persistent place in the pop culture zeitgeist. The beauty in crop formations lies in their underlying precision. Many are built off fractal geometry and repeating mathematical systems, and naturally occurring patterns found throughout science and nature. Even as objects associated with fiction and conspiracy, they are deeply rooted in structure, mathematics, and design. Crop circles are carefully designed spectacles intended to provoke interpretation. Whether read as evidence, artwork, prank, or myth, they reveal how deeply humans want to believe in stories larger than themselves. The cover became less about proving whether something is real or fabricated, and more about exploring the fragile, fascinating space in between. Previous article back to Fact & Fiction Next article

By Gaurika Loomba < Back to Issue 3 Mighty Microscopic Warriors! By Gaurika Loomba 10 September 2022 Edited by Niesha Baker and Khoa-Anh Tran Illustrated by Rachel Ko Next It’s a fine Saturday afternoon. You’re sitting in your backyard sipping on coffee and losing your mind over the daily Wordle. While you’re so engrossed, an unusual, blue-colored creature pulls another chair and solves the Wordle for you. Just as you look up and try to process the condescending smirk of this creature, your daily news notification pops up. It's true! The whole world has been invaded by aliens! Thankfully this is a figment of our imagination, but would you believe me if I told you that alien invasions are constantly happening unnoticed in the microscopic world of our bodies? Every day, our cells face new ‘alien invasions’, thanks to unhygienic eating, or even just from breathing! In the external world, such an invasion would unsettle the entire human population and adversely impact the lives of everyone. It’s amazing how such invasions inside our bodies are usually defeated daily. So who are these tiny ‘soldiers’ that fight them off, silently and efficiently? It’s time to introduce the two brothers of our story– the innate immune cells system and the adaptive immune cells system, the former being the more enthusiastic and energetic one, while the latter is calmer and wiser. Although different in nature, the two systems coordinate efficiently to eliminate our enemies and help us go on about our lives. The innate immune system acts first when a pathogen (a disease-causing microorganism) manages to enter our bodies by getting around our physical barriers like the skin, and the mucus in the respiratory, gastric, urinary, and sexual tracts, etc. The innate immune system consists of cells like macrophages and dendritic cells (DCs), which are constantly looking out for incoming invaders. These cells recognise pathogens through common foreign attributes that our native cells don’t possess. In order to defend us from the harmful effects of the pathogen, our innate cells engulf them. In fact, the word ‘macrophages’ literally means ‘big eaters.’ Inside our cells, the pathogens’ end is inevitable, smashed and broken into pieces, which are mounted on our soldier cells’ surfaces, informing other soldier cells that an invasion has occurred. Exposing broken parts of the pathogen on our innate cells’ surfaces also produces chemicals called cytokines that help recruit more of our soldier cells to the site of invasion. So, when we get flu, the secreted cytokines is why we run a fever, cough, sneeze, and influx of our soldier cells to the throat area is why we may have swelling around there. Similarly, if we bruise, our blood vessels dilate to allow entry of our soldier cells to the wounded area, which is then manifested as redness and swelling around it. Fortunately, this means of communication of our soldier cells is much faster than our internet connection and so the whole process occurs in a matter of hours. On most days, the keen innate immune system is enough to control an invasion. However, it needs big brotherly advice from the adaptive immune system in case things get out of hand. The main players of this part of the immune system are the calm B- and T-cells. These can be found resting in the lymph nodes, unaware of the invasion in the body. The B- and T-cells are wise soldiers, which is evident in the way they respond to an invasion. Each of these cells has molecules called ‘receptors’, which uniquely recognise pathogen parts presented to them. These receptors, on an adaptive cell, can be thought of as padlocks and the broken pathogen parts, mounted on an innate cell, as a key. In the lymph nodes, each resting B- and T-cell has a different type of padlock, unique for a different key. It is the job of a DC, with a broken pathogen part mounted on its surface, to enter the lymph nodes and search for the most accurate match for its key, from the variety of B- and T-cell padlocks. The key varies based on the different types of pathogens that invade our bodies. Once the perfect match is found, that specific B- and T-cell is activated and rapidly multiplied. This lock-and-key method of activation of adaptive cells confers the specificity of their action. These activated cells move from the lymph nodes to the site of infection and perform different functions that halt the pathogen from spreading the disease, by either killing the pathogen or stopping its reproduction. At the site of infection, innate cells, with the key (broken pathogen part) mounted on their surface wait for the brotherly advice, the incoming adaptive cells with the perfect match to the key. The activated T-cells uniquely interact with macrophages and signal them to start killing the pathogens that they have engulfed. This helps with clearance of the pathogen. Although B-cells are part of the adaptive immune system, they can also recognise the foreign pathogen products, break them down, and present these parts on their surface, just like the innate immune cells. So now B-cells also have a key to the activated T-cell padlocks. Their lock-and-key interaction facilitates the B-cells to release antibodies. Finally, the antibodies, together with the macrophages and DCs, as well as the B- and T-cells of the adaptive immune system, successfully win the war and die peacefully, having completed their purpose. But a small portion of B- and T-cells go on and develop into long-lived memory cells. Over the span of our lives, we are infected and reinfected with pathogens all the time, however not every encounter results in us falling sick. The credit goes to the B- and T-memory cells and their ability to remember the foreign attributes of the pathogen and kill it as soon as it re-invades. Adaptive cells’ memory is the principle of vaccination. An inactive pathogen or a part of the pathogen is introduced into the body. This trains our soldier cells for a real pathogen invasion by triggering the B-cells to form memory and specialised antibodies against the pseudo-pathogen. If the real pathogen infects us again, these pre-formed antibodies make fighting the war much easier and quicker. Correct training of immune cells is essential since a pathogen invasion is a life-or-death situation for us. Any mistakes by our soldier cells can have devastating effects. For example, an important part of the training process is to ensure the immune cells aptly distinguish between civilian cells and foreign cells. This education occurs in the bone marrow. Here, any B- or T-cells that attack civilian cells or cell parts are evicted from the training process so only the most eligible soldier cells continue to become eligible soldiers. (1) But even after a rigorous selection process, things can go wrong with our immune system. Instead of being our defending heroes, they turn their back against us and start identifying civilian cells as aliens and attacking them. Sadly, this is the reality for 5% of the Australian population, with a majority being women. This condition, when the immune cells stop distinguishing internal cells from alien cells, is called an auto-immune disorder. The cause for this disorder is mostly unknown, with some speculations of it being genetic or environmental. The repercussions can be mild, such as causing dry mouth and dry eyes - symptoms for Sjogren’s syndrome, or more severe such as joint pain and immobilisation, known as Rheumatoid Arthritis. These diseases are currently life-long and incurable because they involve our own cells fighting the healthy cells in our body. (2) Nevertheless, the immune system plays a very important role in helping us lead normal lives. It fights the battle against the invaders daily, without us realizing it. Thanks to the soldiers of the immune system, our daily activities, like solving a Wordle on a relaxing Saturday, are not hindered by an alien cell invasion in our bodies! References Kenneth Murphy, Casey Weaver. Basic concepts in Immunology. Janeway’s Immunobiology. 9th ed. United States: Garland Science Taylor and Francis; 2017. p. 4-11 Overview of autoimmune diseases [Internet]. Healthdirect. Available from: Overview of autoimmune diseases | healthdirect Previous article Next article alien back to

< Back to Issue 2 Maxing the Vax: why some countries are losing the COVID vaccination race As Australia’s COVID vaccination rate reaches 90% for the adult population, are you aware of countries struggling with their vaccination program? This piece discusses three countries, Brazil, Papua New Guinea, and India, and the key challenges they face in increasing their vaccination rate. by Grace Law 10 December 2021 Edited by Neisha Baker Illustrated by Aisyah Mohammad Sulhanuddin Most Australians are now fully vaccinated against COVID-19, but are you aware of how other countries are handling their vaccination programs? Each country has its own set of challenges and setbacks it must overcome in getting its citizens vaccinated. The success and failure of vaccination programs depend on how well these are addressed, and how the people respond. Political, economic, geographical, and educational factors can have a huge impact on vaccination success. Below, I will discuss the key challenges affecting COVID-19 vaccination in three countries, Brazil, Papua New Guinea, and India, as well as its impact on the country’s vaccination rate. Brazil – the nation that changed their fate Brazil has suffered the highest overall death toll in Latin America which is also the second-highest in the world after the United States. Brazil’s President Jair Bolsonaro was strongly opposed to lockdowns, restrictions, and public-health measures such as masks, which some local areas sought to impose (1). He has also spread disinformation regarding the coronavirus and vaccines, such as posting a video falsely associating the coronavirus vaccines with the onset of AIDS, resulting in Facebook removing it after public outcry (2). As a leader, his words and actions have major roles in influencing opinion and informing the public. While the number of preventable deaths is shocking, the predicted wave of destruction by the Delta variant has not materialised. Over 60% of the population is fully vaccinated despite the mixed messages and deterrence from the central government (3). The city of Serrana became the testing site of the Chinese vaccine Sinovac with most adults being willing towards receiving the vaccine (4). Consequently, the symptomatic cases, hospitalisation and deaths in the area all fell dramatically, becoming a place of envy for the neighbouring communities (5). This initial success also offers hope for low and middle-income countries, which may rely on this cheaper vaccine (6). Despite governmental resistance throughout the pandemic, Brazilians have defied the odds and faced the virus as a united community. Local leaders have challenged the national government to ensure suitable public health orders are enforced, and citizens have actively sought vaccination, preventing further COVID-19 devastation. Papua New Guinea – our struggling neighbour One of Australia’s closest neighbours, Papua New Guinea (PNG), is among the countries with the lowest vaccination rate in the world. According to Our World in Data, only 2% of the population is fully vaccinated (7). One of the most difficult issues to address is mistrust in the vaccine, due to low health education, inadequate health and general resources, and a political and historical distrust in the government. PNG relies on Australia and New Zealand’s AstraZeneca donations to acquire COVID vaccines, as well as Australian embassy staff to help run pop-up clinics in shopping centres. A Chinese medical team has also been working outside the government to unofficially administer the Sinopharm vaccine at a hospital clinic, leading to speculations of politically-motivated manipulation and interference (8). PNG is caught between two great powers, and the already sceptical PNG people are neglected and uninformed about vaccine efficacy, safety, and choices (9). Low science literacy and mistrust in political institutions have made it extremely difficult to convince people to get vaccinated (10). This has furthered the development of conspiracy theories, which interplay with cultural beliefs around witchcraft and superstitions (11). Despite the recent introduction of the “no jab, no job” policy, people are turning to mass resignations or the acquisition of fraudulent certificates instead of receiving the COVID-19 vaccine (12). Australia recently offered aviation lift services to high priority provinces, delivering much-needed emergency supplies to geographically isolated areas in PNG (13). A lot of work is still needed in order to increase the vaccination uptake rate in PNG. Stronger and more impactful campaign messaging will be required to increase public demand for vaccines (14). Foreign aid and assistance should prioritise effective vaccination and long-term health improvement over political agenda (15). The priority must be to stop the pandemic devastation by getting people vaccinated, and addressing long-term infrastructure, funding, and governance issues. India – great challenges and great ambitions India has the second-largest population in the world and it has struggled to source an adequate number of vaccines for its people. The government was ambitious that local manufacturing of the Indian vaccine Covaxin would be sufficient for domestic consumption. Instead, Bharat Biotech’s newest facility in Bengaluru reports quality issues in its initial batches, leading to a delay and vaccine shortage (16). During the country’s destructive second wave from April to June of 2021, the vaccine shortage was exacerbated by the government hesitating to approve vaccines developed and manufactured overseas. Local supply was also hindered by raw material shortages at the beginning of 2021 (17). While the government has sought higher vaccine administrations, setbacks including delays in manufacture, lack of doses received from overseas, and difficulties in obtaining regulatory approval, have contributed to the delayed and restricted nature of the vaccination program. Initially, the people met the vaccination program with great enthusiasm, and the government aimed to vaccinate all adults against COVID-19 by 31 December 2021. But vaccine uptake has plateaued and declined since October, and there are fears this target will not be met. Many factors have contributed to the decreased vaccine uptake, including vaccine shortage, barriers to vaccination such as lockdowns, high infection rates causing fear of visiting vaccination centres, and misinformation particularly in under-resourced rural areas (18). Although an improved COVID-19 vaccination program could have reduced the severity of the second wave, attention now is on maintaining the vaccination uptake rate. As the Indian government started to offer free vaccinations to all adults, citizens living in poverty have had the chance to be vaccinated as well. While many countries wish to manufacture their own vaccines at a fraction of the cost of the pharmaceutical giants, quality control and quality assurance remain incredibly complex issues to tackle (19). Lower-income countries require sufficient guidance and support, and Shahid Jameel, a virologist from Ashoka University in New Delhi says, ‘We can’t fix vaccine inequalities until vaccine manufacturing is distributed.’ (20) Conclusion Numerous factors impact vaccine uptake, with each country facing its own set of challenges. Mismanagement, limited infrastructure, and rampant misinformation were highlighted here, but there are many problems impacting vaccination programs around the world. Urgently addressing these problems will be needed to reduce vaccination inequality around the world, and hopefully, reach the end of the pandemic very soon. For more information on COVID-19 and the vaccine, please visit the VaxFACTS website created by the University of Melbourne: https://www.vaxfacts.org.au/ References Jake Horton, “Covid Brazil: Why could Bolsonaro face charges?” BBC News, published 27 October, 2021, https://www.bbc.com/news/world-latin-america-56663217. “Facebook removes video in which Brazil’s Bolsonaro links coronavirus vaccines with AIDS,” Washington Post, published 25 October, 2021, https://www.washingtonpost.com/technology/2021/10/25/facebook-papers-live-updates/#link-UA7IQVP5E5D2VGUQX7OJQBCFIE. “Coronavirus (COVID-19) Vaccinations,” Our World in Data, published 26 November, 2021, https://ourworldindata.org/covid-vaccinations?country=OWID_WRL. Mauricio Savarese, “Sinovac vaccine restores a Brazilian city to near normal,” Associated Press News, published 2 June, 2021, https://apnews.com/article/caribbean-brazil-coronavirus-pandemic-business-health-20bd94d28ac7b373d7a8f3f9c557e5b6. “Sinovac vaccine restores a Brazilian city to near normal.” “Sinovac vaccine restores a Brazilian city to near normal.” “Coronavirus (COVID-19) Vaccinations.” Natalie Whiting, “PNG caught in China-Australia power play as COVID-19 Delta variant infiltrates Pacific nation,” ABC News, published 2 August, 2021, https://www.abc.net.au/news/2021-08-02/png-caught-between-australia-and-china-as-it-fights-delta/100329206. “PNG caught in China-Australia power play as COVID-19 Delta variant infiltrates Pacific nation.” Mihai Sora, “Overcoming community resistance to vaccination in Papua New Guinea,” The Interpreter, published 26 October, 2021, https://www.lowyinstitute.org/the-interpreter/overcoming-community-resistance-vaccination-papua-new-guinea. Liam Fox and Marian Faa, “Health workers face death threats as COVID-19 vaccine hesitancy takes hold in PNG,” ABC News, published 10 September, 2021, https://www.abc.net.au/news/2021-09-10/png-vaccine-hesitancy-papua-new-guinea-covid-19/100444380. Fraser Macdonald, “Just 1.7 per cent of PNG residents are vaccinated against COVID. Why are they so resistant?” SBS News, published 8 November, 2021, https://www.sbs.com.au/news/just-1-7-per-cent-of-png-residents-are-vaccinated-against-covid-why-are-they-so-resistant/72c40029-dec8-4202-b436-31562d983fbc. “COVID-19 partnership with Papua New Guinea strengthened” Minister for Foreign Affairs, published 27 October, 2021, https://www.foreignminister.gov.au/minister/marise-payne/media-release/covid-19-partnership-papua-new-guinea-strengthened. “Overcoming community resistance to vaccination in Papua New Guinea.” “Overcoming community resistance to vaccination in Papua New Guinea.” Sreenivasan Jain, “Quality Issues Behind Covaxin Shortage: Government vaccine panel chief,” New Delhi Television, published 2 August, 2021, https://www.ndtv.com/india-news/quality-issues-behind-covaxin-shortage-government-vaccine-panel-chief-2500998. Shruti Menon, “India vaccination: Does it have enough doses for all adults?” BBC News, published 3 August, 2021, https://www.bbc.com/news/world-asia-india-55571793. Liji Thomas, “Factors predicrting vaccine hesitancy in India,” News Medical, published 26 September, 2021, https://www.news-medical.net/news/20210926/Factors-predicting-vaccine-hesitancy-in-India.aspx. Amy Maxmen, “The fight to manufacture COVID vaccine in lower-income countries,” Nature, published 16 September, 2021, https://www.nature.com/articles/d41586-021-02383-z. “The fight to manufacture COVID vaccine in lower-income countries.” Previous article back to DISORDER Next article